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Plasma 50 %-life of codeine and its metabolites have already been described to be around 3 hrs . Clearance90 % ved samtidig bruk av rifampicin, at den reduseres med ca. 70 % ved samtidig bruk av rifapentin (daglig dosering), og at den reduseres med thirty-forty % samtidig bruk av rifabutin. Siden den induserende effekten av rifapentin er doseavheng

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